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Maintaining a healthy weight is crucial, especially for people who have diabetes. Not only does carrying extra pounds make it harder to manage blood sugar levels, but certain medications used to treat diabetes can also lead to weight gain. This can create a vicious cycle that makes managing diabetes even more challenging. It’s important to understand which medications are more likely to cause weight gain so you can have informed discussions with your healthcare provider. Fortunately, there are also weight-neutral alternatives that can be just as effective at managing diabetes without the unwanted side effect of packing on the pounds. Some of the medications most commonly associated with weight gain include insulin, sulfonylureas, and thiazolidinediones. Insulin is a hormone that helps regulate blood sugar levels, but when taken in high doses, it can lead to weight gain as your body stores excess glucose as fat. Sulfonylureas and thiazolidinediones also have been shown to increase appetite and cause weight gain in some people. But don’t despair, there are alternative medications available that are less likely to cause weight gain. Glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter 2 (SGLT-2) inhibitors are all weight-neutral options that can help manage blood sugar levels without causing unwanted weight gain. It’s important to note that medication isn’t the only factor that can influence weight gain in people with diabetes. Diet and physical activity can also play a significant role. Making healthy food choices (such as opting for fresh fruits and vegetables instead of processed foods) and engaging in regular exercise can help you maintain a healthy weight and better manage your diabetes. In addition to medication and lifestyle changes, it can also be helpful to have a supportive healthcare team that understands the challenges of living with diabetes. Your healthcare provider can work with you to develop a customized treatment plan that takes into account your unique needs and preferences. Overall, it’s important to be proactive when it comes to managing diabetes and avoiding unwanted weight gain. By understanding which medications are most likely to cause weight gain and exploring weight-neutral alternatives, you can take control of your health and work towards a healthier, happier life.

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